Clinical Significance of High Mobility Group Box 1 Expression in Inflammation of Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome

To clarify clinical significance of high mobility group box 1 level in inflammation asthma-chronic obstructive pulmonary disease overlap syndrome. A total 124 asthma patients acute attack (asthma group), chronic exacerbation (chronic group) and syndrome (asthma-chronic hospitalized the department geriatric respiratory medicine second our hospital from January 2020 to June 2022 were enrolled. The C-reactive protein level, white blood cell counts concentration measured compared three groups. relation serum or was assessed through Pearson correlation. forced expiratory volume % predicted 1/forced vital capacity general data presented no difference among groups (p>0.05). elevation relative those (p<0.05). a positive association with negative High specimens patient’s presents marked elevation, suggesting that has crucial diagnosis therapy